ea0035p1060 | Thyroid (non-cancer) | ECE2014
Pawlik-Pachucka Eliza
, Budzinska Monika
, Domaszewska-Szostek Anna
, Owczarz Magdalena
, Gewartowska Magdalena
, Kurylowicz Alina
, Puzianowska-Kuznicka Monika
Introduction: Decreased function of the thyroid axis during aging is associated with a better functional performance and longer survival. This phenomenon can be a result not only of a lower production of thyroid hormones including bioavailable triiodothyronine, but also of age-associated alterations regarding triiodothyronine receptors.Methods: Functional studies regarding interaction between the 3′UTR of TRβ1 mRNA and in silico-ident...